G176D (p.Gly176Asp) variant of TLR9 (Toll-like receptor 9)
G176D (p.Gly176Asp) in TLR9 (Toll-like receptor 9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
G176D (p.Gly176Asp) variant details
- p.Gly176Asp
- NCI-TCGA Cosmic COSV5972
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.28
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available