F32L (p.Phe32Leu) variant of TLR9 (Toll-like receptor 9)
F32L (p.Phe32Leu) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
F32L (p.Phe32Leu) variant details
- p.Phe32Leu
- ESP rs367677799
- ExAC rs367677799
- TOPMed rs367677799
- gnomAD rs367677799
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.33
- CADD 23.70
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available