E126G (p.Glu126Gly) variant of TLR9 (Toll-like receptor 9)
E126G (p.Glu126Gly) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
E126G (p.Glu126Gly) variant details
- p.Glu126Gly
- gnomAD rs1350834332
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.17
- CADD 24.70
- PolyPhen-2 0.96
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available