E115Q (p.Glu115Gln) variant of TLR9 (Toll-like receptor 9)
E115Q (p.Glu115Gln) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
E115Q (p.Glu115Gln) variant details
- p.Glu115Gln
- 1000Genomes rs184563116
- ExAC rs184563116
- TOPMed rs184563116
- gnomAD rs184563116
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.09
- CADD 19.00
- PolyPhen-2 0.94
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available