E115K (p.Glu115Lys) variant of TLR9 (Toll-like receptor 9)
E115K (p.Glu115Lys) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
E115K (p.Glu115Lys) variant details
- p.Glu115Lys
- 1000Genomes rs184563116
- ExAC rs184563116
- TOPMed rs184563116
- gnomAD rs184563116
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.17
- CADD 22.90
- PolyPhen-2 0.72
- SIFT 0.03
- Most common in the 1KG:FIN population (allele frequency 0.0051)
- Structural context available