A60T (p.Ala60Thr) variant of TLR9 (Toll-like receptor 9)
A60T (p.Ala60Thr) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A60T (p.Ala60Thr) variant details
- p.Ala60Thr
- ESP rs374677585
- ExAC rs374677585
- gnomAD rs374677585
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.06
- CADD 11.00
- PolyPhen-2 0.17
- SIFT 0.24
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available