A187E (p.Ala187Glu) variant of TLR9 (Toll-like receptor 9)
A187E (p.Ala187Glu) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A187E (p.Ala187Glu) variant details
- p.Ala187Glu
- ExAC rs750300739
- gnomAD rs750300739
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.14
- CADD 14.60
- PolyPhen-2 0.04
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 2.6e-05)
- Structural context available