A168V (p.Ala168Val) variant of TLR9 (Toll-like receptor 9)
A168V (p.Ala168Val) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A168V (p.Ala168Val) variant details
- p.Ala168Val
- 1000Genomes rs201098493
- ExAC rs201098493
- TOPMed rs201098493
- gnomAD rs201098493
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.08
- CADD 13.00
- PolyPhen-2 0.22
- SIFT 0.45
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available