A164D (p.Ala164Asp) variant of TLR9 (Toll-like receptor 9)
A164D (p.Ala164Asp) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A164D (p.Ala164Asp) variant details
- p.Ala164Asp
- ExAC rs763686449
- gnomAD rs763686449
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.21
- CADD 5.78
- PolyPhen-2 0.20
- SIFT 0.42
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available