A161T (p.Ala161Thr) variant of TLR9 (Toll-like receptor 9)
A161T (p.Ala161Thr) in TLR9 (Toll-like receptor 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
A161T (p.Ala161Thr) variant details
- p.Ala161Thr
- TOPMed rs1298778487
- gnomAD rs1298778487
- Missense
- Variant Prioritization Score for Impact Estimate 0.0448
- REVEL 0.02
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available