Y64H (p.Tyr64His) variant of TLR8 (Toll-like receptor 8)
Y64H (p.Tyr64His) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
Y64H (p.Tyr64His) variant details
- p.Tyr64His
- gnomAD X-12919230-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.13
- MetaLR 0.07
- MetaSVM -0.91
- CADD 14.70
- PolyPhen-2 0.70
- SIFT 0.35
- Population evidence available
- Structural context available
- Literature evidence available