Y34H (p.Tyr34His) variant of TLR8 (Toll-like receptor 8)
Y34H (p.Tyr34His) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
Y34H (p.Tyr34His) variant details
- p.Tyr34His
- gnomAD X-12919140-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.12
- MetaLR 0.13
- MetaSVM -0.96
- CADD 23.10
- PolyPhen-2 0.85
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available