V65L (p.Val65Leu) variant of TLR8 (Toll-like receptor 8)
V65L (p.Val65Leu) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
V65L (p.Val65Leu) variant details
- p.Val65Leu
- gnomAD X-12919233-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.15
- MetaLR 0.00
- MetaSVM -0.81
- CADD 24.20
- PolyPhen-2 0.97
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available