V57G (p.Val57Gly) variant of TLR8 (Toll-like receptor 8)
V57G (p.Val57Gly) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
V57G (p.Val57Gly) variant details
- p.Val57Gly
- gnomAD X-12919210-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.42
- MetaLR 0.21
- MetaSVM -0.76
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available