V57F (p.Val57Phe) variant of TLR8 (Toll-like receptor 8)
V57F (p.Val57Phe) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
V57F (p.Val57Phe) variant details
- p.Val57Phe
- gnomAD X-12919209-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.30
- MetaLR 0.17
- MetaSVM -0.76
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available