T90P (p.Thr90Pro) variant of TLR8 (Toll-like receptor 8)
T90P (p.Thr90Pro) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
T90P (p.Thr90Pro) variant details
- p.Thr90Pro
- gnomAD X-12919308-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.30
- MetaLR 0.38
- MetaSVM -0.52
- CADD 23.10
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available