T60M (p.Thr60Met) variant of TLR8 (Toll-like receptor 8)
T60M (p.Thr60Met) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
T60M (p.Thr60Met) variant details
- p.Thr60Met
- 1000Genomes rs57166818
- ExAC rs57166818
- gnomAD rs57166818
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.06
- MetaLR 0.07
- MetaSVM -1.04
- CADD 16.50
- PolyPhen-2 0.15
- SIFT 0.10
- Most common in the 1KG:YRI population (allele frequency 0.0058)
- Structural context available