S71P (p.Ser71Pro) variant of TLR8 (Toll-like receptor 8)
S71P (p.Ser71Pro) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
S71P (p.Ser71Pro) variant details
- p.Ser71Pro
- Ensembl rs2043077036
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.33
- MetaLR 0.29
- MetaSVM -0.51
- CADD 24.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available