S33N (p.Ser33Asn) variant of TLR8 (Toll-like receptor 8)
S33N (p.Ser33Asn) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
S33N (p.Ser33Asn) variant details
- p.Ser33Asn
- gnomAD X-12919138-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.07
- CADD 14.60
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available
- Literature evidence available