S19A (p.Ser19Ala) variant of TLR8 (Toll-like receptor 8)
S19A (p.Ser19Ala) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
S19A (p.Ser19Ala) variant details
- p.Ser19Ala
- gnomAD rs1324053224
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.01
- MetaLR 0.05
- MetaSVM -1.02
- CADD 2.81
- PolyPhen-2 0.01
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 1.4e-05)
- Structural context available