Q84R (p.Gln84Arg) variant of TLR8 (Toll-like receptor 8)
Q84R (p.Gln84Arg) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
Q84R (p.Gln84Arg) variant details
- p.Gln84Arg
- TOPMed rs1463697894
- gnomAD rs1463697894
- Missense
- Variant Prioritization Score for Impact Estimate 0.115
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -1.03
- CADD 13.80
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 3.2e-05)
- Structural context available