Q41H (p.Gln41His) variant of TLR8 (Toll-like receptor 8)
Q41H (p.Gln41His) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
Q41H (p.Gln41His) variant details
- p.Gln41His
- ESP rs371285063
- ExAC rs371285063
- TOPMed rs371285063
- gnomAD rs371285063
- Missense
- Variant Prioritization Score for Impact Estimate 0.0606
- REVEL 0.01
- MetaLR 0.04
- MetaSVM -1.05
- CADD 1.73
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 0.00016)
- Structural context available