N99K (p.Asn99Lys) variant of TLR8 (Toll-like receptor 8)
N99K (p.Asn99Lys) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
N99K (p.Asn99Lys) variant details
- p.Asn99Lys
- cosmic curated COSV54320
- TOPMed rs994032756
- gnomAD rs994032756
- Missense
- Variant Prioritization Score for Impact Estimate 0.0598
- REVEL 0.01
- MetaLR 0.00
- MetaSVM -0.92
- CADD 0.22
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00017)
- Structural context available