N95D (p.Asn95Asp) variant of TLR8 (Toll-like receptor 8)
N95D (p.Asn95Asp) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
N95D (p.Asn95Asp) variant details
- p.Asn95Asp
- gnomAD X-12919323-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.37
- MetaLR 0.18
- MetaSVM -0.59
- CADD 22.40
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available