N29K (p.Asn29Lys) variant of TLR8 (Toll-like receptor 8)
N29K (p.Asn29Lys) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
N29K (p.Asn29Lys) variant details
- p.Asn29Lys
- gnomAD X-12919127-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.01
- MetaLR 0.05
- MetaSVM -1.02
- CADD 0.53
- PolyPhen-2 0.11
- SIFT 0.85
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available