M10V (p.Met10Val) variant of TLR8 (Toll-like receptor 8)
M10V (p.Met10Val) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
M10V (p.Met10Val) variant details
- p.Met10Val
- rs5744077
- UniProt VAR 024667
- 1000Genomes rs5744077
- ESP rs5744077
- Missense
- Variant Prioritization Score for Impact Estimate 0.0739
- REVEL 0.04
- MetaLR 0.00
- MetaSVM -1.03
- CADD 0.02
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the 1KG:ESN population (allele frequency 0.17)
- Structural context available