L94L (p.Leu94Leu) variant of TLR8 (Toll-like receptor 8)
L94L (p.Leu94Leu) in TLR8 (Toll-like receptor 8) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L94L (p.Leu94Leu) variant details
- p.Leu94Leu
- rs1176445876
- gnomAD X-12919320-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.398
- CADD 7.30
- Most common in the Ashkenazi Jewish population (allele frequency 0.00038)
- Structural context available
- Literature evidence available