L89P (p.Leu89Pro) variant of TLR8 (Toll-like receptor 8)
L89P (p.Leu89Pro) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
L89P (p.Leu89Pro) variant details
- p.Leu89Pro
- gnomAD X-12919306-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.67
- REVEL 0.71
- MetaLR 0.74
- MetaSVM 0.71
- CADD 24.50
- PolyPhen-2 0.79
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available