L24I (p.Leu24Ile) variant of TLR8 (Toll-like receptor 8)
L24I (p.Leu24Ile) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
L24I (p.Leu24Ile) variant details
- p.Leu24Ile
- ESP rs139980479
- ExAC rs139980479
- TOPMed rs139980479
- gnomAD rs139980479
- Missense
- Variant Prioritization Score for Impact Estimate 0.0639
- REVEL 0.01
- MetaLR 0.05
- MetaSVM -1.06
- CADD 0.89
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.5e-05)
- Structural context available