L17Q (p.Leu17Gln) variant of TLR8 (Toll-like receptor 8)
L17Q (p.Leu17Gln) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
L17Q (p.Leu17Gln) variant details
- p.Leu17Gln
- gnomAD X-12919090-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.24
- MetaLR 0.15
- MetaSVM -0.87
- CADD 22.40
- PolyPhen-2 0.83
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available