L17I (p.Leu17Ile) variant of TLR8 (Toll-like receptor 8)
L17I (p.Leu17Ile) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L17I (p.Leu17Ile) variant details
- p.Leu17Ile
- gnomAD X-12919089-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.04
- CADD 12.20
- PolyPhen-2 0.01
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available