L11M (p.Leu11Met) variant of TLR8 (Toll-like receptor 8)
L11M (p.Leu11Met) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
L11M (p.Leu11Met) variant details
- p.Leu11Met
- gnomAD X-12919071-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.11
- MetaLR 0.07
- MetaSVM -1.05
- CADD 16.10
- PolyPhen-2 0.69
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available