K40E (p.Lys40Glu) variant of TLR8 (Toll-like receptor 8)
K40E (p.Lys40Glu) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
K40E (p.Lys40Glu) variant details
- p.Lys40Glu
- gnomAD X-12919158-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.04
- MetaLR 0.05
- MetaSVM -1.01
- CADD 6.61
- PolyPhen-2 0.01
- SIFT 0.97
- Population evidence available
- Structural context available
- Literature evidence available