K39E (p.Lys39Glu) variant of TLR8 (Toll-like receptor 8)
K39E (p.Lys39Glu) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
K39E (p.Lys39Glu) variant details
- p.Lys39Glu
- gnomAD X-12910428-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- CADD 5.17
- SIFT 0.69
- Most common in the Middle Eastern population (allele frequency 0.00024)
- Structural context available
- Literature evidence available