I78V (p.Ile78Val) variant of TLR8 (Toll-like receptor 8)
I78V (p.Ile78Val) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I78V (p.Ile78Val) variant details
- p.Ile78Val
- TOPMed rs1159957082
- gnomAD rs1159957082
- Missense
- Variant Prioritization Score for Impact Estimate 0.0779
- REVEL 0.02
- MetaLR 0.12
- MetaSVM -1.00
- CADD 2.26
- PolyPhen-2 0.14
- SIFT 0.22
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.5e-05)
- Structural context available