I46V (p.Ile46Val) variant of TLR8 (Toll-like receptor 8)
I46V (p.Ile46Val) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
I46V (p.Ile46Val) variant details
- p.Ile46Val
- gnomAD X-12919176-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0692
- REVEL 0.02
- MetaLR 0.06
- MetaSVM -1.06
- CADD 0.70
- PolyPhen-2 0.07
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available