H96R (p.His96Arg) variant of TLR8 (Toll-like receptor 8)
H96R (p.His96Arg) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
H96R (p.His96Arg) variant details
- p.His96Arg
- gnomAD X-12919327-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.01
- MetaLR 0.09
- MetaSVM -1.03
- CADD 13.90
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available