G85R (p.Gly85Arg) variant of TLR8 (Toll-like receptor 8)
G85R (p.Gly85Arg) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
G85R (p.Gly85Arg) variant details
- p.Gly85Arg
- gnomAD X-12919293-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.07
- MetaLR 0.10
- MetaSVM -0.99
- CADD 14.00
- PolyPhen-2 0.11
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available