G85E (p.Gly85Glu) variant of TLR8 (Toll-like receptor 8)
G85E (p.Gly85Glu) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
G85E (p.Gly85Glu) variant details
- p.Gly85Glu
- gnomAD X-12919294-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.07
- MetaLR 0.14
- MetaSVM -0.99
- CADD 13.10
- PolyPhen-2 0.07
- SIFT 0.39
- Population evidence available
- Structural context available
- Literature evidence available