G20V (p.Gly20Val) variant of TLR8 (Toll-like receptor 8)
G20V (p.Gly20Val) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
G20V (p.Gly20Val) variant details
- p.Gly20Val
- gnomAD rs866448188
- Missense
- Variant Prioritization Score for Impact Estimate 0.0741
- REVEL 0.03
- MetaLR 0.04
- MetaSVM -1.05
- CADD 0.35
- PolyPhen-2 0.21
- SIFT 0.57
- Most common in the South Asian population (allele frequency 1.9e-05)
- Structural context available