G20D (p.Gly20Asp) variant of TLR8 (Toll-like receptor 8)
G20D (p.Gly20Asp) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
G20D (p.Gly20Asp) variant details
- p.Gly20Asp
- cosmic curated COSV54317
- gnomAD rs866448188
- Missense
- Variant Prioritization Score for Impact Estimate 0.0714
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.01
- CADD 0.28
- PolyPhen-2 0.01
- SIFT 0.62
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00017)
- Structural context available