F15I (p.Phe15Ile) variant of TLR8 (Toll-like receptor 8)
F15I (p.Phe15Ile) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F15I (p.Phe15Ile) variant details
- p.Phe15Ile
- cosmic curated COSV99028
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.04
- MetaLR 0.04
- MetaSVM -1.03
- CADD 9.32
- PolyPhen-2 0.04
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available