E38D (p.Glu38Asp) variant of TLR8 (Toll-like receptor 8)
E38D (p.Glu38Asp) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
E38D (p.Glu38Asp) variant details
- p.Glu38Asp
- gnomAD rs1417335127
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -1.04
- CADD 15.00
- PolyPhen-2 0.44
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available