D72N (p.Asp72Asn) variant of TLR8 (Toll-like receptor 8)
D72N (p.Asp72Asn) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
D72N (p.Asp72Asn) variant details
- p.Asp72Asn
- ExAC rs778375164
- gnomAD rs778375164
- Missense
- Variant Prioritization Score for Impact Estimate 0.0969
- REVEL 0.07
- MetaLR 0.04
- MetaSVM -1.01
- CADD 2.57
- PolyPhen-2 0.02
- SIFT 0.57
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available