D72G (p.Asp72Gly) variant of TLR8 (Toll-like receptor 8)
D72G (p.Asp72Gly) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
D72G (p.Asp72Gly) variant details
- p.Asp72Gly
- gnomAD X-12919255-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.09
- MetaLR 0.05
- MetaSVM -1.00
- CADD 7.87
- PolyPhen-2 0.02
- SIFT 0.43
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available