D43G (p.Asp43Gly) variant of TLR8 (Toll-like receptor 8)
D43G (p.Asp43Gly) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
D43G (p.Asp43Gly) variant details
- p.Asp43Gly
- gnomAD rs1326691885
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.09
- MetaLR 0.03
- MetaSVM -1.02
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.57
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available