D37V (p.Asp37Val) variant of TLR8 (Toll-like receptor 8)
D37V (p.Asp37Val) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
D37V (p.Asp37Val) variant details
- p.Asp37Val
- gnomAD X-12919150-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.17
- MetaLR 0.22
- MetaSVM -0.90
- CADD 22.90
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.9e-06)
- Structural context available
- Literature evidence available