D37H (p.Asp37His) variant of TLR8 (Toll-like receptor 8)
D37H (p.Asp37His) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
D37H (p.Asp37His) variant details
- p.Asp37His
- gnomAD X-12919149-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.09
- MetaLR 0.22
- MetaSVM -0.92
- CADD 21.40
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available