C36G (p.Cys36Gly) variant of TLR8 (Toll-like receptor 8)
C36G (p.Cys36Gly) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
C36G (p.Cys36Gly) variant details
- p.Cys36Gly
- gnomAD X-12919146-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.52
- MetaLR 0.30
- MetaSVM -0.41
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available