C13R (p.Cys13Arg) variant of TLR8 (Toll-like receptor 8)
C13R (p.Cys13Arg) in TLR8 (Toll-like receptor 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
C13R (p.Cys13Arg) variant details
- p.Cys13Arg
- gnomAD X-12919077-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.14
- MetaLR 0.05
- MetaSVM -1.10
- CADD 19.30
- PolyPhen-2 0.29
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available